Description

Adenosine N1-Oxide-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling. This specialized analog is designed for advanced biochemical and pharmacological research, offering unique properties for studying purinergic signaling pathways and enzyme interactions. It is primarily utilized by research institutions and pharmaceutical developers in the fields of molecular biology, signal transduction research, and drug discovery.

Application

• Biochemical Research: As a stable analog for investigating cAMP-dependent protein kinase (PKA) activation and related signal transduction mechanisms.
• Pharmaceutical Development: Serves as a reference standard or a key intermediate in the synthesis of novel therapeutic agents targeting cardiovascular and neurological systems.
• Enzyme Studies: Used as a substrate or inhibitor in assays for phosphodiesterases (PDEs) and other enzymes involved in nucleotide metabolism.
• Cell Signaling Pathways: A critical tool for modulating intracellular cAMP levels to study effects on cell growth, differentiation, and apoptosis.
• Academic Research: Fundamental studies in universities and institutes exploring the role of oxidized nucleotides in cellular physiology and oxidative stress responses.

Basic Information

Product Name	Adenosine N1-Oxide-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	75912-25-3
Molecular Formula	C10H11N5NaO8P
Molecular Weight	391.19 g/mol
Synonyms	cAMP N1-Oxide Sodium Salt; Adenosine 3',5'-cyclic monophosphate N1-oxide sodium salt; 8-Azaxanthosine 3',5'-cyclic monophosphate sodium salt (related analog); N1-Oxido-cAMP sodium salt; Cyclic AMP N-oxide sodium salt; Sodium 9-β-D-ribofuranosylpurine-1-oxide-3',5'-cyclic phosphate; 1-Oxoadenosine 3',5'-cyclic monophosphate sodium salt
EINECS	Contact for details

Quality Control

Our Adenosine N1-Oxide-3',5'-Cyclic Monophosphate Sodium Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Custom synthesis and purification to meet specific project requirements are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.