Description

D-Ribitol, 5-S-(3-Amino-3-Carboxypropyl)-1-C-(7-Amino-1H-Pyrazolo(4,3-D)Pyrimidin-3-Yl)-1,4-Anhydro-5-Thio-, (1S,5(S))- is a sophisticated, high-purity nucleoside analog derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard for the synthesis and study of modified nucleic acids and enzyme inhibitors. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleic acid chemistry, antiviral drug discovery, and enzymology. Our supply ensures consistent quality and reliable availability for your most demanding R&D and process development projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving tRNA modification enzymes and other nucleoside-processing proteins.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Nucleic Acid Chemistry: Employed in the research and development of modified oligonucleotides with tailored biological properties.
• Mechanistic Studies: Utilized to investigate metabolic pathways and the mechanism of action of related therapeutic compounds.
• Process Development: Acts as a critical raw material for scaling up the production of specialized active pharmaceutical ingredients (APIs).

Basic Information

Product Name	D-Ribitol, 5-S-(3-Amino-3-Carboxypropyl)-1-C-(7-Amino-1H-Pyrazolo(4,3-D)Pyrimidin-3-Yl)-1,4-Anhydro-5-Thio-, (1S,5(S))-
CAS No.	75899-14-8
Molecular Formula	C14H20N6O5S
Molecular Weight	384.41 g/mol
Synonyms	7-Amino-3-(1,4-anhydro-5-thio-D-ribitol-1-yl)-1H-pyrazolo[4,3-d]pyrimidine-5-carboxylic acid; 3-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-thio-D-ribitol derivative; Modified Nucleoside Derivative; tRNA Nucleoside Q Precursor; (1S,5S)-1-(7-Amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-5-thio-D-ribitol-5-yl-3-aminopropanoic acid; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of this advanced biochemical is produced and analyzed under strict quality management protocols to ensure identity, purity, and consistency. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay purity and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.