Description

11,20-Dihydroxy-3-Oxo-4-Pregnen-21-Oic Acid is a high-purity steroid derivative and a key synthetic intermediate in pharmaceutical research and development. This compound is valued for its role in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and reference standards. It is primarily sought by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutics, particularly in the fields of endocrinology and anti-inflammatory drugs.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced corticosteroid and other steroid-based APIs.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related steroid compounds.
• Biochemical Research: Serves as a precursor or substrate in studies investigating steroid metabolism, enzyme activity, and receptor binding.
• Process Development: Employed in scaling up and optimizing synthetic routes for steroid production within R&D and pilot plant settings.

Basic Information

Product Name	11,20-Dihydroxy-3-Oxo-4-Pregnen-21-Oic Acid
CAS No.	75879-79-7
Molecular Formula	C21H30O5
Molecular Weight	362.46 g/mol
Synonyms	11β,20-Dihydroxy-3-oxopregn-4-ene-21-carboxylic acid; 11β,20-Dihydroxy-3-oxo-4-pregnene-21-carboxylic acid; 11β,20α-Dihydroxy-3-oxo-4-pregnene-21-carboxylic acid; 11β-Hydroxy-20-oxo-3-oxopregn-4-ene-21-oic acid (tautomeric form); 11β,20-Dihydroxy-21-nor-3-oxopregn-4-ene-21-carboxylic acid; Pregnen-21-oic acid derivative; Steroid intermediate 75879-79-7
EINECS	Contact for details

Quality Control

Our 11,20-Dihydroxy-3-Oxo-4-Pregnen-21-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.