Description

(20R)-20-Hydroxy-24-Methylene-5α-Dammaran-3-One CAS NO 75872-02-5 is a high-purity, semi-synthetic triterpenoid derivative of dammarane, a key structural motif found in bioactive natural products. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile reference standard for analytical and research purposes. It is essential for manufacturers and R&D teams in the pharmaceutical, nutraceutical, and fine chemical sectors who require a reliable, high-quality building block for the synthesis of complex molecules targeting metabolic and inflammatory pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in metabolic and anti-inflammatory drug discovery.
• Reference Standard: Used as a certified standard for quality control (QC) and analytical method development in HPLC, LC-MS, and NMR for related dammarane compounds.
• Nutraceutical Research: Serves as a precursor or model compound in the study of bioactive triterpenoids for dietary supplements and functional foods.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists exploring the structure-activity relationships (SAR) of tetracyclic triterpenoids.
• Biochemical Research: Used in enzymatic studies and as a substrate or inhibitor probe for investigating biological pathways involving sterol-like molecules.

Basic Information

Product Name	(20R)-20-Hydroxy-24-Methylene-5α-Dammaran-3-One
CAS No.	75872-02-5
Molecular Formula	C₃₁H₅₂O₂
Molecular Weight	456.75 g/mol
Synonyms	24-Methylene-20-hydroxy-5α-dammaran-3-one; (20R)-20-Hydroxy-24-methylenedammaran-3-one; 20-Hydroxy-24-methylenedammar-3-one; Dammarane-3-one, 20-hydroxy-24-methylene-, (5α,20R)-; 75872-02-5; 24-Methylenedammaran-3-one, 20-hydroxy-; 5α-Dammaran-3-one, 20-hydroxy-24-methylene-, (20R)-
EINECS	Contact for details

Quality Control

Our (20R)-20-Hydroxy-24-Methylene-5α-Dammaran-3-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D and reference material applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (20R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.