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2,5-Difluorobenzyl Alcohol CAS NO 75853-20-2


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CAS No.:75853-20-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,5-Difluorobenzyl Alcohol is a versatile fluorinated aromatic alcohol building block, essential for introducing the difluorobenzyl moiety into complex molecular architectures. Its value lies in its role as a key intermediate in the synthesis of advanced pharmaceutical compounds and agrochemicals, where the fluorine atoms enhance metabolic stability and bioavailability. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug candidates.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the difluorobenzyl group contributes to efficacy and environmental profile.
  • Liquid Crystal Materials: Serves as a precursor in the production of fluorinated compounds for electronic display applications.
  • Organic Synthesis & Research: A valuable reagent for introducing fluorinated benzyl protecting groups or for further functionalization in medicinal chemistry and material science research.
  • Fine Chemical Production: Employed in the manufacture of specialty chemicals, including dyes, pigments, and advanced polymers.

Basic Information

Product Name 2,5-Difluorobenzyl Alcohol
CAS No. 75853-20-2
Molecular Formula C7H6F2O
Molecular Weight 144.12 g/mol
Synonyms (2,5-Difluorophenyl)methanol; 2,5-Difluorobenzenemethanol; α,2,5-Trifluorotoluene; 2,5-Difluorobenzylalcohol; 1-(Hydroxymethyl)-2,5-difluorobenzene; 2,5-Difluoro Benzyl Alcohol; 2,5-DFBA
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Quality Control

Our 2,5-Difluorobenzyl Alcohol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to minimize exposure to moisture and air.

Specification

Item Specification
Appearance Colorless to pale yellow liquid or crystalline solid
Identification (IR) Conforms to structure
Assay (HPLC/GC) ≥98.0%
Water Content (KF) ≤0.5%
Related Substances (HPLC) Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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