Description

4-Isoxazolecarbonyl Chloride, 5-Butyl- (9Ci) is a specialized organic intermediate belonging to the isoxazole family, characterized by its reactive carbonyl chloride functional group. This compound is a critical building block in synthetic organic chemistry, enabling the efficient introduction of the 5-butylisoxazole moiety into more complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and advanced materials. Its precise structure offers unique reactivity for creating targeted molecules with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly for candidates with isoxazole-based scaffolds.
• Agrochemical Development: Used in creating novel herbicides, fungicides, and insecticides where the isoxazole ring contributes to biological activity.
• Material Science Research: Acts as a monomer or coupling agent in the development of specialized polymers and functional materials.
• Chemical Synthesis: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds and in medicinal chemistry campaigns.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands or organocatalysts containing the isoxazole functional group.

Basic Information

Product Name	4-Isoxazolecarbonyl Chloride, 5-Butyl- (9Ci)
CAS No.	75706-00-2
Molecular Formula	C8H10ClNO2
Molecular Weight	187.62 g/mol
Synonyms	5-Butylisoxazole-4-carbonyl chloride; 5-Butyl-4-isoxazolecarbonyl chloride; 4-Isoxazolecarbonyl chloride, 5-butyl-; 5-n-Butylisoxazole-4-carboxylic acid chloride; 5-Butyl-1,2-oxazole-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 4-Isoxazolecarbonyl Chloride, 5-Butyl- (9Ci) is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to meet the high standards required for synthetic intermediates. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical range 95-98%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.