Description

1-(2-Deoxy-β-D-Ribofuranosyl)-5-(Methylmercapto)-2-Pyrimidinone is a modified nucleoside derivative, a key building block in medicinal chemistry and life science research. Its core value lies in its role as a versatile synthetic intermediate for the development of novel antiviral and anticancer agents, particularly in the design of nucleoside analogs. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, specialized intermediates for advanced therapeutic development.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel nucleoside analog drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the R&D of potential therapeutics for a range of DNA and RNA viruses.
• Anticancer Agent Development: Serves as a building block for creating prodrugs and targeted chemotherapeutic compounds.
• Biochemical Research: Employed in studies of enzyme mechanisms, DNA/RNA metabolism, and cellular signaling pathways.
• Proteomics & Genomics: Used as a modified base in oligonucleotide synthesis for diagnostic probes and research tools.
• Fine Chemical Synthesis: Intermediate for creating complex, high-value specialty chemicals with biological activity.

Basic Information

Product Name	1-(2-Deoxy-β-D-Ribofuranosyl)-5-(Methylmercapto)-2-Pyrimidinone
CAS No.	75670-13-2
Molecular Formula	C10H14N2O4S
Molecular Weight	258.29 g/mol
Synonyms	5-(Methylthio)-2'-deoxyuridine; 5-Methylmercapto-2'-deoxyuridine; 5-Methylthio-2'-deoxyuridine; 5-(Methylsulfanyl)-2'-deoxyuridine; 1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methylsulfanyl)pyrimidin-2-one; 5-S-Methyl-2'-deoxyuridine; 5-Methylmercapto-2'-deoxyuridine; d5SMeU
EINECS	Contact for details

Quality Control

Our 1-(2-Deoxy-β-D-Ribofuranosyl)-5-(Methylmercapto)-2-Pyrimidinone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.