Description

3-Dodecylsulfonyl-2-Methylpropionyl Chloride is a specialized organic intermediate featuring a reactive acid chloride group and a long-chain sulfonyl moiety. This compound matters for its role as a key building block in the synthesis of complex molecules, enabling the introduction of lipophilic and sulfonyl functionalities. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical reagent for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or long alkyl chain modifications.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where its structure can contribute to lipid membrane interaction and bioavailability.
• Polymer Modification: Serves as a functional monomer or cross-linking agent to introduce specific sulfonyl and ester groups into polymer backbones, altering material properties.
• Surface Active Agent Precursor: Acts as a key intermediate in the manufacture of specialized surfactants and emulsifiers with unique hydrophobic-hydrophilic balance.
• Liquid Crystal & OLED Material Research: Employed in the development of advanced organic electronic materials due to its potential for creating ordered molecular structures.
• Chemical Biology & Proteomics: Useful as a labeling or cross-linking reagent for modifying proteins and studying biomolecular interactions.

Basic Information

Product Name	3-Dodecylsulfonyl-2-Methylpropionyl Chloride
CAS No.	75654-72-7
Molecular Formula	C₁₆H₃₁ClO₃S
Molecular Weight	338.93 g/mol
Synonyms	2-Methyl-3-(dodecylsulfonyl)propionyl chloride; 3-(Dodecylsulfonyl)-2-methylpropanoic acid chloride; 2-Methyl-3-(sulfonyldodecyl)propionyl chloride; Dodecylsulfonylmethylpropionyl chloride; NSC 405122; Propionyl chloride, 3-(dodecylsulfonyl)-2-methyl-; 3-(Dodecylsulfonyl)-2-methylpropanoyl chloride
EINECS	Contact for details

Quality Control

Our 3-Dodecylsulfonyl-2-Methylpropionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.