Description

2H-Pyran-6-Carbonyl Chloride, 2-Oxo- (9Ci) is a highly reactive and versatile chemical intermediate, specifically an acid chloride derivative of a pyranone. This compound matters for its role as a key building block in advanced organic synthesis, enabling the efficient introduction of the 2-oxo-2H-pyran-6-carbonyl moiety. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those containing pyran or pyridone-like heterocyclic structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where specific heterocyclic motifs are required for bioactivity.
• Material Science Research: Serves as a monomer or precursor for developing functional polymers and organic electronic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling biomolecules or synthesizing activity-based probes for enzyme studies.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fragrance ingredients, dyes, and other high-value specialty chemicals.

Basic Information

Item	Details
Product Name	2H-Pyran-6-Carbonyl Chloride, 2-Oxo- (9Ci)
CAS No.	75611-67-5
Molecular Formula	C6H3ClO3
Molecular Weight	158.54 g/mol
Synonyms	2-Oxo-2H-pyran-6-carbonyl chloride; 6-Chlorocarbonyl-2H-pyran-2-one; 2-Oxo-2H-pyran-6-carboxylic acid chloride; 6-(Chlorocarbonyl)-2H-pyran-2-one; 2H-Pyran-2-one, 6-carbonyl chloride; 6-Pyron-2-carboxylic acid chloride; Penta-2,4-dien-4-olide-6-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 2H-Pyran-6-Carbonyl Chloride, 2-Oxo- (9Ci) is produced and tested under stringent quality management protocols to ensure consistency and reliability for your synthetic workflows. We provide comprehensive analytical data, including HPLC purity, NMR, and IR spectroscopy for structural confirmation. A detailed Certificate of Analysis (COA) is supplied with each shipment, and custom purity grades or analytical packages are available to meet specific research or cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Standard Grade)
Water Content (KF)	≤ 1.0%
Solubility Test	Soluble in common organic solvents (e.g., THF, DCM, Acetonitrile)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.