Description

Cytidine 5'-Triphosphate, Periodate Oxidized Sodium Salt is a chemically modified nucleotide derivative where the ribose sugar moiety has been selectively oxidized by periodate. This modification is critical for its role as a key intermediate and reagent in advanced biochemical research and synthesis. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications requiring specific, non-hydrolyzable nucleotide analogs. This product is supplied as a high-purity sodium salt, optimized for stability and performance in sensitive experimental protocols.

Application

• Biochemical Research: Essential as a substrate analog in enzymatic studies, particularly for RNA polymerases and other nucleotide-dependent enzymes, to investigate reaction mechanisms and inhibition.
• Probe Synthesis: Used in the preparation of non-radioactive or fluorescently labeled probes for nucleic acid detection and hybridization assays.
• Cross-linking Agent: The periodate-oxidized triphosphate group can serve as a reactive handle for cross-linking proteins to nucleic acids or for affinity labeling.
• Pharmaceutical Intermediate: Acts as a specialized building block in the research and development of novel antiviral or anticancer nucleotide-based therapeutics.
• Diagnostic Kit Manufacturing: Incorporated into the formulation of high-sensitivity diagnostic kits for pathogen detection and genetic testing.
• Enzyme Characterization: Employed to study the binding sites and catalytic properties of kinases, synthetases, and other ATP/GTP-utilizing enzymes.

Basic Information

Product Name	Cytidine 5'-Triphosphate, Periodate Oxidized Sodium Salt
CAS No.	75567-73-6
Molecular Formula	C9H13N3O15P3Nax (x~3)
Molecular Weight	Approx. 605.1 (as free acid, C9H16N3O15P3)
Synonyms	Periodate-Oxidized CTP; Oxidized Cytidine Triphosphate; CTP-IO4; 2'-(or 3')-O-(4-Amino-4-carboxybutyl)cytidine 5'-triphosphate precursor; Sodium 5'-O-{hydroxy[oxido(phosphonatooxy)phosphoryl]phosphoryl}cytidine-2',3'-dialdehyde; CTP dialdehyde; Reactive CTP analog; cCTP-ox
EINECS	Contact for details

Quality Control

Our Cytidine 5'-Triphosphate, Periodate Oxidized Sodium Salt is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for research and in-vitro diagnostic use. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for characterization. While produced to high standards, this product is currently intended for research purposes and is not for drug, food, or household use.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 10 EU/mg (if specified)
Biological Activity	Tested in functional enzymatic assay (results on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.