Description

Moxonidine (Hydrochloride) CAS NO 75536-04-8 is a high-purity pharmaceutical active ingredient, specifically a centrally acting imidazoline receptor agonist. It is a critical compound for the development and production of antihypertensive medications, offering a selective mechanism of action. This product is essential for pharmaceutical manufacturers, research institutions, and laboratories engaged in cardiovascular drug formulation, generic drug development, and advanced pharmacological studies.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of prescription antihypertensive and anti-hypertensive medications.
• Generic Drug Manufacturing: Serves as the key component for producing generic versions of branded moxonidine-based therapies.
• Research & Development: Used in preclinical and clinical studies for investigating new cardiovascular treatments and combination therapies.
• Reference Standard: Employed as a high-purity standard in analytical laboratories for quality control (HPLC, LC-MS) and method validation.
• Biochemical Research: Utilized in studies focusing on imidazoline receptors and central nervous system-mediated blood pressure regulation.
• Formulation Development: Integral to the development of various dosage forms such as tablets and controlled-release formulations.

Basic Information

Product Name	Moxonidine (Hydrochloride)
CAS No.	75536-04-8
Molecular Formula	C9H12ClN5O • HCl
Molecular Weight	278.14 g/mol
Synonyms	4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine hydrochloride; Moxonidine HCl; BDF 5895; LU 20884; CYNT; Physiotens; Moxon
EINECS	Contact for details

Quality Control

Our Moxonidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide detailed Certificates of Analysis (COA) that include identity, purity, and impurity profiles, supporting compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.