Description

Moxonidine Hydrochloride CAS NO 75438-58-3 is a high-purity pharmaceutical active ingredient (API) belonging to the class of centrally-acting antihypertensive agents. It is a critical intermediate and final active substance for the formulation of modern cardiovascular medications. This compound is primarily required by pharmaceutical manufacturers and advanced research institutions for the development and production of antihypertensive drugs.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of finished dosage forms for hypertension treatment.
• Antihypertensive Drug Formulation: Used in tablets, capsules, and other solid oral dosage forms.
• Cardiovascular Research: Reference standard and key material in pharmacological and clinical research studies.
• Generic Drug Production: Essential for the synthesis of generic versions of branded moxonidine medications.
• Analytical Standard: Serves as a high-purity standard for quality control and assay development in analytical laboratories.
• Preclinical Development: Used in stability studies, pharmacokinetic profiling, and toxicology assessments.

Basic Information

Product Name	Moxonidine Hydrochloride
CAS No.	75438-58-3
Molecular Formula	C9H12ClN5O • HCl
Molecular Weight	278.14 g/mol
Synonyms	4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamine hydrochloride; Moxonidine HCl; BDF 5895; LU 20884; Physiotens (brand name); Cynt (brand name); 4-Chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-ylamino)pyrimidine hydrochloride
EINECS	Contact for details

Quality Control

Our Moxonidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent pharmaceutical-grade specifications, including identity, purity, and impurity profile. Certificates of Analysis (COA) confirming compliance with relevant standards are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.