Description

Miconazole Nitrate CAS NO 75319-48-1 is a synthetic imidazole antifungal agent, widely recognized for its broad-spectrum activity against pathogenic fungi and yeasts. Its primary value lies in its potent efficacy and stability, making it a cornerstone active pharmaceutical ingredient (API) for topical and systemic antifungal formulations. This compound is essential for pharmaceutical manufacturers developing treatments for dermatological infections, oral thrush, and other fungal conditions.

Application

• Pharmaceutical API: Primary active ingredient in topical creams, ointments, powders, and sprays for athlete's foot, ringworm, jock itch, and cutaneous candidiasis.
• Oral Gel Formulations: Used in medicated gels and lozenges for the treatment of oropharyngeal candidiasis (oral thrush).
• Veterinary Medicine: Incorporated into antifungal preparations for treating skin and hoof infections in livestock and companion animals.
• Personal Care Products: Key component in antifungal soaps, medicated shampoos, and foot care products.
• Industrial Preservative: Potential use as a fungistatic agent in certain industrial applications to prevent microbial spoilage.

Basic Information

Product Name	Miconazole Nitrate
CAS No.	75319-48-1
Molecular Formula	C18H14Cl4N2O·HNO3
Molecular Weight	479.15 g/mol
Synonyms	Miconazole Nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate; Micatin (trade name); Monistat (trade name); Daktarin (trade name); Gyno-Daktarin; Miconazole mononitrate; R 14889 (research code)
EINECS	278-155-6

Quality Control

Our Miconazole Nitrate is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP, EP, and BP. Each batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water (KF Titration)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.