Description

Fully Protected Deoxynucleotide Dimerd(A Pap) is a specialized, high-purity building block essential for oligonucleotide synthesis. This compound matters because it provides the critical, chemically protected monomer units required for the automated assembly of DNA and RNA sequences with high fidelity and yield. It is primarily needed by research institutions, pharmaceutical developers, and diagnostic companies engaged in molecular biology, antisense therapy development, and PCR probe manufacturing.

Application

• Oligonucleotide Synthesis: As a phosphoramidite precursor for the solid-phase automated synthesis of DNA and RNA strands.
• Antisense & siRNA Therapeutics: A key raw material in the production of therapeutic oligonucleotides for gene silencing and targeted treatments.
• PCR & Molecular Diagnostics: Used in the manufacture of primers, probes, and other essential components for diagnostic assays and genetic testing.
• Genomic Research: Enables the study of gene function, expression, and regulation through the creation of custom DNA fragments.
• Next-Generation Sequencing (NGS): Employed in the preparation of sequencing libraries and custom oligo pools.
• CRISPR-Cas9 System Components: Used for synthesizing guide RNAs (gRNAs) and other oligonucleotide tools for genome editing.

Basic Information

Product Name	Fully Protected Deoxynucleotide Dimerd(A Pap)
CAS No.	75269-16-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	d(ApAp) Phosphoramidite; N6-Benzoyl-2'-deoxyadenylyl-(3'→5')-2'-deoxyadenosine, 5'-O-(4,4'-Dimethoxytrityl)-, 3'-[2-Cyanoethyl N,N-Diisopropylphosphoramidite]; 5'-O-DMT-N6-benzoyl-2'-deoxyadenylyl-(3'→5')-N6-benzoyl-2'-deoxyadenosine 3'-O-(2-cyanoethyl N,N-diisopropylphosphoramidite); Fully Protected d(ApA) Dimer; d(ApA) CE Phosphoramidite; DMT-d(ApA(Bz))-CE Phosphoramidite
EINECS	Contact for details

Quality Control

Our Fully Protected Deoxynucleotide Dimerd(A Pap) is manufactured under strict quality systems to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, moisture content, and performance data is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (argon or nitrogen) in a dry, moisture-free environment. Due to its hygroscopic nature, allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or foam
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Moisture Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.