Description

1(Beta)-D-Arabinofuranosylcytosine-5'-Diphosphate Prednisolone is a sophisticated, high-purity biochemical conjugate designed for advanced research and development. This compound matters as a critical tool for investigating novel therapeutic pathways, combining the mechanisms of a nucleoside diphosphate with a potent glucocorticoid. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, immunology, and targeted drug delivery systems.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel anti-cancer and anti-inflammatory prodrugs.
• Biochemical Mechanism Studies: Used to investigate cellular signaling pathways, nucleotide metabolism, and steroid-receptor interactions in controlled laboratory settings.
• Targeted Drug Delivery Prototyping: Explored in the design of conjugates that aim to deliver prednisolone specifically to cancer cells via nucleoside transport mechanisms.
• Enzymology Research: Acts as a potential substrate or inhibitor in studies involving kinases, phosphorylases, and other enzymes that process nucleotide-sugar conjugates.
• Reference Standard for Analytical Labs: Provides a high-purity benchmark for quality control and method development in HPLC, LC-MS, and NMR analysis.

Basic Information

Item	Details
Product Name	1(Beta)-D-Arabinofuranosylcytosine-5'-Diphosphate Prednisolone
CAS No.	75252-35-6
Molecular Formula	C31H40N3O16P2
Molecular Weight	780.62 g/mol
Synonyms	Prednisolone Cytarabine Diphosphate; Ara-CDP-Prednisolone; Cytarabine 5'-Diphosphate Prednisolone Ester; 1-β-D-Arabinofuranosylcytosine 5'-diphosphate prednisolone-21-ester; 5'-DP-Prednisolone Cytarabine Conjugate; NSC-129220 (related); Prednisolone-21-cytidine-5'-diphosphate
EINECS	Contact for details

Quality Control

Our 1(Beta)-D-Arabinofuranosylcytosine-5'-Diphosphate Prednisolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research applications. Certificates of Analysis (COA) detailing purity, impurities, and analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.