Description

Guanosine 3'-Triphosphoric Acid CAS NO 75228-09-0 is a high-purity nucleotide triphosphate derivative, a critical building block for RNA synthesis and a key substrate in enzymatic reactions. Its primary value lies in its role as a specialized reagent for biochemical research, molecular biology, and diagnostic assay development. This compound is essential for industries and research institutions focused on nucleic acid synthesis, enzyme kinetics studies, and high-throughput screening applications.

Application

• Biochemical Research & Enzymology: As a specific substrate for RNA polymerases, kinases, and GTP-binding proteins (G-proteins) in mechanistic studies.
• Molecular Biology: Used in in vitro transcription systems for the synthesis of specific RNA sequences and probes.
• Diagnostic Assay Development: A key component in luminescence-based assays (e.g., luciferase reporter assays) and other detection methodologies requiring GTP.
• Pharmaceutical R&D: Employed in screening platforms for drug discovery targeting GTPase and kinase pathways.
• Cell Signaling Studies: Essential for investigating cellular signal transduction mechanisms involving GTP-binding proteins.
• Reference Standard: Serves as a high-purity analytical standard for quality control in nucleotide manufacturing and research.

Basic Information

Product Name	Guanosine 3'-Triphosphoric Acid
CAS No.	75228-09-0
Molecular Formula	C10H16N5O14P3
Molecular Weight	523.18 g/mol
Synonyms	3'-GTP; Guanosine-3'-triphosphate; 3'-Guanosine triphosphate; GTP (3' isomer); 9-β-D-Ribofuranosylguanine 3'-(trihydrogen triphosphate); Guanosine 3'-(tetrahydrogen triphosphate); 3'-Guanilyl triphosphate
EINECS	Contact for details

Quality Control

Our Guanosine 3'-Triphosphoric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and diagnostic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (Karl Fischer)	≤ 5.0%
pH (in solution)	Contact for details
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.