Description

6-Bromo-3-Chloro-Benzo[B]Thiophene-2-Carbonyl Chloride is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive acid chloride group and halogenated benzothiophene scaffold, enabling precise molecular construction in complex chemical environments. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its rigid, conjugated structure.
• Chemical Biology Probes: Employed in the creation of fluorescent tags and molecular probes for studying biological pathways.
• Cross-Coupling Reactions: The bromo and chloro substituents make it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	6-Bromo-3-Chloro-Benzo[B]Thiophene-2-Carbonyl Chloride
CAS No.	75212-27-0
Molecular Formula	C9H3BrCl2OS
Molecular Weight	310.00 g/mol
Synonyms	6-Bromo-3-chlorobenzo[b]thiophene-2-carbonyl chloride; 2-Benzothiophenecarbonyl chloride, 6-bromo-3-chloro-; 3-Chloro-6-bromobenzo[b]thiophene-2-carbonyl chloride; 6-Bromo-3-chloro-2-benzothienecarbonyl chloride; 6-Bromo-3-chloro-1-benzothiophene-2-carbonyl chloride; 75212-27-0; Benzo[b]thiophene-2-carbonyl chloride, 6-bromo-3-chloro-
EINECS	Contact for details

Quality Control

Our 6-Bromo-3-Chloro-Benzo[B]Thiophene-2-Carbonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.