Description

(3A,5B,6B,7B,12A)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid CAS NO 75110-48-4 is a high-purity, polyhydroxylated bile acid derivative, a key intermediate in the synthesis of complex pharmaceutical compounds. Its precise stereochemistry and functional group array make it a valuable building block for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on metabolic and liver disease research.

Application

• Pharmaceutical Intermediate: Critical starting material or precursor in the synthesis of novel therapeutic agents, particularly those targeting metabolic pathways.
• Biochemical Research: Used as a reference standard or probe in studies of bile acid metabolism, liver function, and membrane transport mechanisms.
• Medicinal Chemistry: Serves as a scaffold for the development of new drug candidates due to its specific hydroxyl group configuration and cholanic acid backbone.
• Reference Standard: Employed in analytical laboratories for method development, calibration, and quality control testing of related compounds.
• Fine Chemical Synthesis: A versatile chiral synthon for the production of other specialized, high-value chemical entities.

Basic Information

Product Name	(3A,5B,6B,7B,12A)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid
CAS No.	75110-48-4
Molecular Formula	C₂₄H₄₀O₆
Molecular Weight	424.57 g/mol
Synonyms	3α,6α,7α,12α-Tetrahydroxy-5β-cholan-24-oic Acid; 3α,6α,7α,12α-Tetrahydroxy-5β-cholanoic Acid; Tetrahydroxycholanic Acid; Hyocholic Acid (3α,6α,7α,12α-isomer); 5β-Cholan-24-oic acid, 3α,6α,7α,12α-tetrahydroxy-; Hyocholic Acid (alpha isomer)
EINECS	Contact for details

Quality Control

Our (3A,5B,6B,7B,12A)-3,6,7,12-Tetrahydroxy-Cholan-24-Oic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.