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3-Azido-1,2-Di-o-Acetyl-5-o-(4-Methylbenzoyl)-3-Deoxy-β-D-Ribofuranose CAS NO 75096-64-9


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CAS No.:75096-64-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Azido-1,2-Di-o-Acetyl-5-o-(4-Methylbenzoyl)-3-Deoxy-β-D-Ribofuranose is a sophisticated, protected ribofuranose derivative, serving as a critical synthetic intermediate in modern organic and medicinal chemistry. Its value lies in its functionalized structure, which provides a versatile scaffold for the controlled synthesis of nucleoside analogs and other bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity building blocks for drug discovery and development.

Application

  • Nucleoside Analog Synthesis: A key protected intermediate for the preparation of modified nucleosides with potential antiviral or anticancer activity.
  • Pharmaceutical Research & Development: Used in the discovery and synthesis of novel therapeutic agents targeting viral infections and genetic disorders.
  • Bioconjugation & Probe Development: The azido group enables efficient "click chemistry" reactions (e.g., CuAAC) for labeling biomolecules or creating chemical probes.
  • Carbohydrate Chemistry: A valuable substrate for studying glycosylation reactions and synthesizing complex oligosaccharide mimetics.
  • Fine Chemical Intermediate: Employed in custom synthesis and contract manufacturing for producing high-value specialty chemicals.

Basic Information

Item Detail
Product Name 3-Azido-1,2-Di-o-Acetyl-5-o-(4-Methylbenzoyl)-3-Deoxy-β-D-Ribofuranose
CAS No. 75096-64-9
Molecular Formula C17H19N3O7
Molecular Weight 377.35 g/mol
Synonyms 1,2-Di-O-acetyl-5-O-(4-methylbenzoyl)-3-azido-3-deoxy-β-D-ribofuranose; 3-Azido-3-deoxy-1,2-di-O-acetyl-5-O-p-toluoyl-β-D-ribofuranose; 3-Azido-1,2-di-O-acetyl-5-O-(p-toluoyl)-3-deoxy-β-D-ribofuranose; 3-Deoxy-3-azido-1,2-di-O-acetyl-5-O-(4-methylbenzoyl)-β-D-ribofuranose; β-D-Ribofuranose, 3-azido-1,2-di-O-acetyl-5-O-(4-methylbenzoyl)-3-deoxy-; Protected 3-Azidoribofuranose; p-Toluoyl-protected azido ribose intermediate
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Quality Control

Our production of 3-Azido-1,2-Di-o-Acetyl-5-o-(4-Methylbenzoyl)-3-Deoxy-β-D-Ribofuranose adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee the material meets your specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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