Description

Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride, Stereoisomer (9Ci) is a high-value, strained bicyclic building block featuring two reactive acid chloride functionalities. This compound matters as a key chiral synthon for constructing complex three-dimensional molecular architectures in advanced pharmaceutical and materials research. It is primarily needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers where its unique rigid scaffold can impart desirable physicochemical properties. The product is supplied with a CAS number of 74985-46-9.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its bicyclic structure can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer & Material Science: Employed as a monomer or cross-linking agent for developing high-performance polymers with enhanced thermal stability and mechanical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, enabling access to complex, strained carbocyclic systems.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride, Stereoisomer (9Ci)
CAS No.	74985-46-9
Molecular Formula	C8H6Cl2O2
Molecular Weight	205.04 g/mol
Synonyms	5,6-Bicyclo[2.1.1]hexanedicarbonyl dichloride; Bicyclo[2.1.1]hexane-5,6-dicarboxylic acid dichloride; 5,6-Dicarboxybicyclo[2.1.1]hexane dichloride; (1S,4S)-Bicyclo[2.1.1]hexane-5,6-dicarbonyl dichloride; (1R,4R)-Bicyclo[2.1.1]hexane-5,6-dicarbonyl dichloride; Bicyclo[2.1.1]hexane-5,6-dicarboxylic dichloride; 74985-46-9; Bicyclo[2.1.1]hexane dicarbonyl dichloride stereoisomer
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride, Stereoisomer (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and chiral purity analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) and store at temperatures between 2°C and 8°C for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.