Description

Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride, Stereoisomer (9Ci) is a highly reactive and synthetically valuable bicyclic acid chloride derivative, serving as a critical building block for advanced organic synthesis. Its unique strained bicyclo[2.1.1]hexane scaffold is prized for introducing three-dimensional complexity and structural rigidity into target molecules, which is essential for modulating physical and biological properties. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing novel drug candidates, particularly those requiring conformationally constrained, three-dimensional architectures to improve target binding and metabolic stability.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the bicyclic core can enhance efficacy and environmental profile.
• Material Science Monomer: Serves as a reactive monomer for producing specialty polymers with unique thermal and mechanical properties due to its rigid, strained ring system.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes and tags with enhanced rigidity for studying biological systems and protein-ligand interactions.
• Cross-Coupling Reactions: Functions as an electrophilic coupling partner in various metal-catalyzed cross-coupling reactions to construct complex carbon frameworks.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride, Stereoisomer (9Ci)
CAS No.	74965-19-8
Molecular Formula	C8H6Cl2O2
Molecular Weight	205.04 g/mol
Synonyms	5,6-Bicyclo[2.1.1]hexanedicarbonyl dichloride; Bicyclo[2.1.1]hexane-5,6-dicarboxylic acid dichloride; 5,6-Dicarboxybicyclo[2.1.1]hexane dichloride; 1,4-Dichlorocarbonylbicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexane-1,4-dicarbonyl dichloride; (1s,4s)-Bicyclo[2.1.1]hexane-1,4-dicarbonyl dichloride (for specific stereoisomer); BCHDC
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.1.1]Hexane-5,6-Dicarbonyl Dichloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity suitable for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity, and relevant physical data is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Stereoisomer Ratio	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.