Description

Cholesteryl Eicosapentaenoate is a high-purity ester formed from cholesterol and the ω-3 fatty acid eicosapentaenoic acid (EPA). This compound is of significant interest for advanced research and development in the pharmaceutical and nutraceutical sectors, particularly for studying lipid metabolism and developing novel drug delivery systems. It is primarily utilized by R&D laboratories, specialty chemical manufacturers, and formulators working on lipid-based therapeutics, functional food ingredients, and high-end cosmetic actives.

Application

• Pharmaceutical Research: A key intermediate or reference standard in the development of novel lipid-based drug delivery systems (e.g., liposomes, nanoparticles) and for studying cholesterol metabolism.
• Nutraceutical Formulation: Used in advanced dietary supplement research as a potential carrier for enhancing the bioavailability and targeted delivery of ω-3 fatty acids.
• Biochemical Studies: Serves as a critical reagent in cell biology and biochemistry labs for membrane fluidity studies, lipid raft research, and investigating the role of specific lipid esters in cellular processes.
• Cosmetic Science: Investigated for use in high-performance skincare formulations for its potential skin-barrier repair and anti-inflammatory properties derived from its EPA component.
• Reference Standard: Employed as an analytical standard in HPLC, GC, and LC-MS methods for the quantification of cholesterol esters in complex biological matrices.
• Lipidomics: An important compound in the field of lipidomics for profiling and understanding the cholesterol ester landscape in health and disease states.

Basic Information

Product Name	Cholesteryl Eicosapentaenoate
CAS No.	74892-97-0
Molecular Formula	C47H74O2
Molecular Weight	671.1 g/mol
Synonyms	Cholesterol Eicosapentaenoate; 5-Cholesten-3β-ol 3-(5,8,11,14,17-eicosapentaenoate); Cholest-5-en-3β-yl (5Z,8Z,11Z,14Z,17Z)-eicosa-5,8,11,14,17-pentaenoate; EPA Cholesterol Ester; (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic Acid Cholesteryl Ester; Cholesteryl EPA; Cholesterol EPA Ester
EINECS	Contact for details

Quality Control

Our Cholesteryl Eicosapentaenoate is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and analytical reference standard customers.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below for long-term stability. For short-term use, store at 2-8°C. This product is easily oxidized and light-sensitive; allow it to reach room temperature in the sealed container before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or oil
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥95.0% (Area %)
Related Substances (HPLC)	Total impurities ≤5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.