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2-[(2,6-Dichloro-3-Methylphenyl)Amino]Benzoic Acid Trimethylsilyl Ester CAS NO 74810-88-1
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CAS No.:74810-88-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-[(2,6-Dichloro-3-Methylphenyl)Amino]Benzoic Acid Trimethylsilyl Ester is a specialized organosilicon derivative of a substituted anthranilic acid, serving as a key protected intermediate in advanced organic synthesis. This compound is valued for its role in facilitating complex chemical transformations where the trimethylsilyl (TMS) group acts as a protective moiety for the carboxylic acid functionality, enhancing solubility and reactivity in non-polar media. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.
Application
- Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
- Agrochemical Synthesis: Used in the development and production of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
- Organic Synthesis Reagent: Serves as a protected carboxylic acid derivative in complex organic reactions, including cross-coupling and nucleophilic substitution.
- Chemical Research: Employed in academic and industrial R&D laboratories for methodological studies and the creation of new chemical entities.
- Fine Chemical Production: Acts as a precursor in the manufacture of specialized dyes, pigments, and performance chemicals.
Basic Information
| Product Name | 2-[(2,6-Dichloro-3-Methylphenyl)Amino]Benzoic Acid Trimethylsilyl Ester |
| CAS No. | 74810-88-1 |
| Molecular Formula | C17H19Cl2NO2Si |
| Molecular Weight | 368.33 g/mol |
| Synonyms | Trimethylsilyl 2-[(2,6-dichloro-3-methylphenyl)amino]benzoate; 2-((2,6-Dichloro-m-tolyl)amino)benzoic Acid Trimethylsilyl Ester; TMS Ester of Diclofenac Acid Derivative; Benzoic acid, 2-[(2,6-dichloro-3-methylphenyl)amino]-, trimethylsilyl ester; (2,6-Dichloro-3-methylphenyl)anthranilic Acid TMS Ester; N-(2,6-Dichloro-3-methylphenyl)anthranilic Acid Trimethylsilyl Ester |
| EINECS | Contact for details |
Quality Control
Our 2-[(2,6-Dichloro-3-Methylphenyl)Amino]Benzoic Acid Trimethylsilyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, purity, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. This material should be stored separately from strong bases and oxidizing agents.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Related Substances (HPLC) | Total impurities ≤ 3.0% |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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