Description

4-Butyl-1,2-Diphenyl-5-[(Trimethylsilyl)Oxy]-1H-Pyrazol-3(2H)-One is a specialized organosilicon-protected pyrazolone derivative, serving as a critical synthetic intermediate and building block in advanced organic synthesis. Its value lies in the strategic protection of the reactive hydroxyl group by the trimethylsilyl (TMS) moiety, which enhances stability and alters reactivity for selective transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in heterocyclic chemistry.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the pyrazolone core structure.
• Organic Synthesis Reagent: Acts as a protected synthon for the controlled introduction of the 5-hydroxy-1H-pyrazol-3(2H)-one moiety into complex molecules.
• Material Science Precursor: Potential intermediate for creating functional organic materials and ligands for metal complexes.
• Academic & R&D: A valuable compound for methodological studies in synthetic organic chemistry, including protection/deprotection strategies.

Basic Information

Item	Detail
Product Name	4-Butyl-1,2-Diphenyl-5-[(Trimethylsilyl)Oxy]-1H-Pyrazol-3(2H)-One
CAS No.	74810-87-0
Molecular Formula	C22H28N2O2Si
Molecular Weight	380.56 g/mol
Synonyms	5-(Trimethylsilyloxy)-4-butyl-1,2-diphenyl-1H-pyrazol-3(2H)-one; 4-Butyl-1,2-diphenyl-5-(trimethylsilyloxy)-1H-pyrazol-3(2H)-one; 1,2-Diphenyl-4-butyl-5-(trimethylsiloxy)pyrazol-3-one; TMS-protected 4-butyl-1,2-diphenylpyrazol-3-one-5-ol; 74810-87-0; 4-n-Butyl-1,2-diphenyl-5-(trimethylsilyloxy)pyrazol-3-one
EINECS	Contact for details

Quality Control

Our production of 4-Butyl-1,2-Diphenyl-5-[(Trimethylsilyl)Oxy]-1H-Pyrazol-3(2H)-One adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.