Description

Acetyl Bromide-2-13C CAS NO 74787-38-5 is a stable isotope-labeled derivative of acetyl bromide, where the carbonyl carbon is specifically enriched with carbon-13. This precise labeling is critical for advanced analytical and synthetic chemistry, providing a non-radioactive tracer for mechanistic studies and metabolic pathway elucidation. It is an essential reagent for researchers and manufacturers in pharmaceutical development, agrochemical research, and advanced material science who require high-fidelity isotopic markers.

Application

• Pharmaceutical Research & Development: As a key carbon-13 labeled building block for synthesizing isotopically labeled drug candidates, metabolites, and internal standards for quantitative bioanalysis (LC-MS/MS).
• Mechanistic Organic Chemistry Studies: Employed in tracer experiments and kinetic isotope effect (KIE) studies to investigate reaction mechanisms, including acylation and Friedel-Crafts reactions.
• Metabolomics & Stable Isotope Probing (SIP): Used to trace carbon flow in complex biological systems for metabolic pathway mapping in microbiological, environmental, and biomedical research.
• NMR Spectroscopy: Serves as a precursor for preparing site-specifically labeled compounds, enhancing signal resolution and simplifying complex NMR spectra for structural analysis.
• Agrochemical Development: Synthesis of labeled pesticide or herbicide analogs for studying environmental fate, degradation pathways, and residue analysis.
• Material Science: Incorporation of carbon-13 labels into polymers or advanced organic materials for structural and dynamic studies using spectroscopic techniques.

Basic Information

Item	Detail
Product Name	Acetyl Bromide-2-13C
CAS No.	74787-38-5
Molecular Formula	¹³CCH3BrO
Molecular Weight	122.94 g/mol (for ¹³C labeled form)
Synonyms	Acetic-2-13C Bromide; (2-13C)Acetyl Bromide; ¹³C-Acetyl Bromide; Ethanoyl-2-13C Bromide; Bromo(2-13C)ethanone; Carbon-13 Labeled Acetyl Bromide; 13C1-Acetyl Bromide; [13C]Acetyl Bromide
EINECS	Contact for details

Quality Control

Every batch of Acetyl Bromide-2-13C is produced and tested under strict quality management protocols. We guarantee high chemical and isotopic purity through comprehensive analytical techniques including NMR, GC-MS, and IR spectroscopy. Certificates of Analysis (COA) are provided with each shipment, detailing assay, isotopic enrichment (typically >99 atom % ¹³C), and impurity profiles. Our quality system ensures traceability and consistency for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and hygroscopic (moisture-sensitive) nature, this product must be stored in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C under an inert atmosphere. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % ¹³C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.