Description

7-(δ-Hydroxybutyl)Guanosine is a chemically modified nucleoside derivative of guanosine, characterized by the addition of a hydroxybutyl side chain at the 7-position. This structural modification is of significant interest for its potential role in advanced biochemical research and pharmaceutical development. It is primarily utilized by research scientists and process developers in the fields of nucleoside chemistry, antiviral research, and medicinal chemistry for exploring novel therapeutic pathways and synthetic analogs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleoside-based antiviral or anticancer drug candidates.
• Biochemical Research: Used as a substrate or reference standard in enzymatic studies and metabolic pathway investigations.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop new therapeutic agents targeting viral polymerases or other nucleoside-binding proteins.
• Process Development: Acts as a critical intermediate in the scale-up and optimization of synthetic routes for complex nucleoside derivatives.
• Academic Research: Utilized in universities and research institutes for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	7-(δ-Hydroxybutyl)Guanosine
CAS No.	74746-57-9
Molecular Formula	C14H19N5O6
Molecular Weight	353.33 g/mol
Synonyms	7-(4-Hydroxybutyl)guanosine; Guanosine, 7-(4-hydroxybutyl)-; 7-(ω-Hydroxybutyl)guanosine; 7-HBG; 7-(4-Hydroxybutyl)-guanosine; 7-(Tetrahydro-2-furanylmethyl)guanosine (related structure); 7-Alkylguanosine derivative
EINECS	Contact for details

Quality Control

Our 7-(δ-Hydroxybutyl)Guanosine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. All materials undergo rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.