Description

n-[4-(2,2,2-Trifluoro-1-Hydroxyethyl)Phenyl]Propionamide is a specialized fluorinated organic compound featuring a trifluoroethanol moiety linked to a phenylpropionamide core. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research institutions and fine chemical manufacturers engaged in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor for advanced herbicides and fungicides, leveraging the stability and bioactivity of the trifluoromethyl group.
• Material Science Research: Used in the synthesis of specialty polymers and liquid crystals where fluorine incorporation enhances thermal stability and chemical resistance.
• Biochemical Tool Compound: Employed in academic and industrial research as a probe or inhibitor to study specific enzymatic pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	n-[4-(2,2,2-Trifluoro-1-Hydroxyethyl)Phenyl]Propionamide
CAS No.	74696-73-4
Molecular Formula	C11H12F3NO2
Molecular Weight	247.21 g/mol
Synonyms	4'-(2,2,2-Trifluoro-1-hydroxyethyl)propiophenone amide; 1-[4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl]-1-propanone amide; N-[4-(2,2,2-Trifluoro-1-hydroxyethyl)phenyl]propanamide; 2,2,2-Trifluoro-1-[4-(propionylamino)phenyl]ethanol; TFHPE Propionamide
EINECS	Contact for details

Quality Control

Our production of n-[4-(2,2,2-Trifluoro-1-Hydroxyethyl)Phenyl]Propionamide adheres to stringent quality management systems. Every batch is analyzed to ensure high chemical purity and consistency, with testing typically including identity confirmation, assay, and impurity profiling. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The product may be hygroscopic; handle in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.