Description

n-4-Azido-2-Nitrophenylnornicotine is a specialized chemical derivative of nornicotine, featuring an azido and a nitro group on the phenyl ring. This compound is valued for its role as a key intermediate and a versatile building block in advanced organic synthesis and biochemical research. It is primarily utilized by research institutions and pharmaceutical development companies working on receptor-targeted studies, photoaffinity labeling, and the synthesis of novel nicotine analogs.

Application

• Photoaffinity Labeling Probes: The azido group makes it a critical reagent for developing photoaffinity labels to study nicotinic acetylcholine receptors (nAChRs) and their binding sites.
• Biochemical Research Intermediate: Serves as a precursor in the synthesis of modified nicotine analogs for structure-activity relationship (SAR) studies.
• Medicinal Chemistry: Used in the research and development of novel therapeutic agents targeting neurological pathways.
• Chemical Biology Tool: Employed in the design of molecular probes for investigating protein-ligand interactions and signal transduction mechanisms.
• Organic Synthesis Building Block: Functions as a versatile intermediate for introducing specific functional groups into complex molecular architectures.

Basic Information

Product Name	n-4-Azido-2-Nitrophenylnornicotine
CAS No.	74660-84-7
Molecular Formula	C₁₆H₁₆N₆O₂
Molecular Weight	324.34 g/mol
Synonyms	4-Azido-2-nitrophenylnornicotine; N-(4-Azido-2-nitrophenyl)nornicotine; ANPNN; 1-(4-Azido-2-nitrophenyl)-2-(3-pyridyl)pyrrolidine; Nornicotine, N-(4-azido-2-nitrophenyl)-; Azidonitrophenylnornicotine
EINECS	Contact for details

Quality Control

Our n-4-Azido-2-Nitrophenylnornicotine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, handling should be performed under subdued light or using amber glassware to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.