Description

S-Benzoyl-3-Mercapto-2-Methylpropanoyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to efficiently introduce the S-benzoyl-3-mercapto-2-methylpropanoyl moiety, enabling the construction of complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, particularly in the development of novel antiviral and anticancer agents.
• Peptide Mimetic Synthesis: Used to incorporate thioester and modified amino acid structures into peptide chains, enhancing stability and bioactivity.
• Agrochemical Research: Intermediate in the production of advanced herbicides and fungicides with novel modes of action.
• Chemical Biology Probes: Facilitates the creation of activity-based probes for studying enzyme function and mechanism.
• Material Science: Potential monomer or cross-linking agent for specialty polymers with unique chemical functionalities.

Basic Information

Product Name	S-Benzoyl-3-Mercapto-2-Methylpropanoyl Chloride
CAS No.	74654-91-4
Molecular Formula	C12H11ClO2S
Molecular Weight	254.73 g/mol
Synonyms	3-(Benzoylthio)-2-methylpropanoyl chloride; 2-Methyl-3-(phenylcarbonothioyl)thio]propanoic acid chloride; S-Benzoyl-β-mercaptoisobutyryl chloride; NSC 339586; (2-Methyl-3-sulfanylpropanoyl) chloride, S-benzoate
EINECS	Contact for details

Quality Control

Our S-Benzoyl-3-Mercapto-2-Methylpropanoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its reactivity as an acid chloride and sensitivity to moisture, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.