Description

1-Azido-2-[2-(2-Methoxyethoxy)Ethoxy]Ethane is a specialized azido-functionalized polyethylene glycol (PEG) derivative, also known as an azido-PEG-ether. This compound matters as a versatile heterobifunctional linker for click chemistry, enabling efficient and selective conjugation of biomolecules, polymers, and surfaces in aqueous and organic media. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and materials science industries for applications such as bioconjugation, surface functionalization, and the synthesis of advanced polymeric materials.

Application

• Bioconjugation Agent: Used in click chemistry (CuAAC or strain-promoted) to link peptides, proteins, antibodies, or oligonucleotides to other molecules, surfaces, or polymeric carriers.
• Polymer & Material Science: Serves as a functional monomer or crosslinker for synthesizing smart polymers, hydrogels, and functionalized nanomaterials with tailored properties.
• Surface Modification: Facilitates the creation of biofunctional coatings on glass, gold, or polymer surfaces for biosensors, microarrays, and diagnostic devices.
• Pharmaceutical Development: Enables the site-specific modification of drug molecules and the development of antibody-drug conjugates (ADCs) and targeted drug delivery systems.
• Chemical Probe Synthesis: A key building block for creating activity-based probes (ABPs) and imaging agents for proteomics and cellular studies.

Basic Information

Product Name	1-Azido-2-[2-(2-Methoxyethoxy)Ethoxy]Ethane
CAS No.	74654-06-1
Molecular Formula	C9H19N3O4
Molecular Weight	233.27 g/mol
Synonyms	Azido-PEG3-methyl ether; 2-[2-(2-Methoxyethoxy)ethoxy]ethyl azide; 11-Azido-3,6,9-trioxaundecan-1-ol methyl ether; 3,6,9-Trioxaundec-10-yl azide; Azido-tri(ethylene glycol) methyl ether; mPEG3-Azide; N3-PEG3-OMe; Azido-PEG-OMe (MW ~233)
EINECS	Contact for details

Quality Control

Our 1-Azido-2-[2-(2-Methoxyethoxy)Ethoxy]Ethane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance for sensitive applications like bioconjugation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C for long-term stability. This compound is light-sensitive and should be handled under inert atmosphere when possible to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.