Description

2H-Isoindole-2-Carbonylchloride,1,3-Dihydro-1-Oxo-(9Ci) is a specialized heterocyclic building block and acid chloride derivative of significant value in advanced organic synthesis. Its core utility lies in its reactivity as an acylating agent, enabling the efficient construction of complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those containing isoindolinone or related heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its reactive carbonyl chloride group facilitates amide bond formation.
• Material Science Research: Employed in the creation of specialty polymers and functional organic materials that require precise molecular design.
• Academic & Contract Research: Serves as a valuable reagent in university laboratories and CROs (Contract Research Organizations) for methodological studies and exploratory chemistry.
• Peptide Mimetic Chemistry: Facilitates the introduction of constrained, heterocyclic structures into peptide chains to modulate biological activity and stability.

Basic Information

Product Name	2H-Isoindole-2-Carbonylchloride,1,3-Dihydro-1-Oxo-(9Ci)
CAS No.	74572-58-0
Molecular Formula	C9H4ClNO2
Molecular Weight	193.59 g/mol
Synonyms	1-Oxo-1,3-dihydro-2H-isoindole-2-carbonyl chloride; 1,3-Dihydro-1-oxo-2H-isoindole-2-carbonyl chloride; Isoindolin-1-one-2-carbonyl chloride; 2-Carboxyisoindolin-1-one acid chloride; 1-Oxoisoindoline-2-carbonyl chloride; 2-(Chlorocarbonyl)isoindolin-1-one; 74572-58-0; 2H-Isoindole-2-carbonyl chloride, 1,3-dihydro-1-oxo-
EINECS	Contact for details

Quality Control

Our 2H-Isoindole-2-Carbonylchloride,1,3-Dihydro-1-Oxo-(9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC for assay and impurity profiling. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.