Description

4-Trimethylsilylbutanoic Acid Potassium Salt is a high-purity organosilicon potassium salt with significant utility in advanced synthetic chemistry. This compound is valued for its role as a versatile building block and protecting group reagent, enabling precise molecular transformations. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those requiring silicon-containing moieties.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the trimethylsilyl group modifies bioavailability or stability.
• Peptide Chemistry: Serves as a protecting group for carboxylic acid functionalities during solid-phase peptide synthesis (SPPS).
• Material Science Research: Employed in the preparation of silicon-based polymers, coatings, and advanced materials.
• Cross-Coupling Reactions: Acts as a reagent in palladium-catalyzed cross-coupling reactions to introduce functionalized alkyl chains.
• Academic & Industrial R&D: A valuable tool for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	4-Trimethylsilylbutanoic Acid Potassium Salt
CAS No.	74427-86-4
Molecular Formula	C7H15KO2Si
Molecular Weight	198.38 g/mol
Synonyms	Potassium 4-(Trimethylsilyl)butanoate; 4-(Trimethylsilyl)butyric Acid Potassium Salt; Butanoic acid, 4-(trimethylsilyl)-, potassium salt (1:1); TMS-Butyric Acid Potassium Salt; (4-Trimethylsilylbutyryloxy)potassium; Potassium 4-trimethylsilylbutyrate; 74427-86-4; 4-TMS-butanoic acid K salt
EINECS	Contact for details

Quality Control

Our 4-Trimethylsilylbutanoic Acid Potassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.