Description

Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Ethyl Ester, cis- (9Ci) is a high-purity, specialized organic ester and acid chloride derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in complex organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing cyclopropane and ester functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the cis-cyclopropane structure imparts specific biological activity.
• Fine Chemical Manufacturing: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring high structural precision.
• Material Science Research: Employed in the development of novel polymers and advanced materials with tailored properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-forming reactions and stereoselective synthesis.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Ethyl Ester, cis- (9Ci)
CAS No.	74408-49-4
Molecular Formula	C9H13ClO3
Molecular Weight	204.65 g/mol
Synonyms	cis-3-(Chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylic acid ethyl ester; Ethyl cis-3-(chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylate; 2,2-Dimethylcyclopropane-1,3-dicarboxylic acid 1-ethyl ester 3-acid chloride (cis); (1R,3S)-3-(Chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylic acid ethyl ester; (1S,3R)-3-(Chlorocarbonyl)-2,2-dimethylcyclopropanecarboxylic acid ethyl ester; cis-2,2-Dimethyl-3-(ethoxycarbonyl)cyclopropanecarbonyl chloride
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 3-(Chlorocarbonyl)-2,2-Dimethyl-, Ethyl Ester, cis- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids and organic solvents; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.