Description

Ibu-Dmt-Deoxyguanosine Succinic Acid is a high-purity, modified nucleoside derivative designed for advanced research and development applications. This compound is critical for scientists working on the synthesis and study of oligonucleotides with specific functional modifications. It serves as a key building block for researchers in the pharmaceutical, biotechnology, and life sciences sectors who require precise molecular tools for drug discovery, diagnostic assay development, and fundamental biochemical studies.

Application

• Oligonucleotide Synthesis: A crucial phosphoramidite precursor for the solid-phase synthesis of modified DNA and RNA strands.
• Antisense & siRNA Research: Used in the development of therapeutic oligonucleotides targeting specific gene expression pathways.
• Diagnostic Probe Development: Incorporated into nucleic acid probes for enhanced detection sensitivity and specificity in assays.
• Bioconjugation & Labeling: Serves as a linker or attachment point for fluorescent dyes, quenchers, or other reporter molecules.
• Structural Biology Studies: Employed to investigate nucleic acid structure, function, and protein-nucleic acid interactions.
• Pharmaceutical Intermediate: Acts as a specialized intermediate in the research and development of novel nucleotide-based therapeutics.

Basic Information

Product Name	Ibu-Dmt-Deoxyguanosine Succinic Acid
CAS No.	74405-46-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(2-Deoxy-β-D-erythro-pentofuranosyl)-N-(3,5-dimethyl-4-isobutyloxybenzoyl)-2'-deoxyguanosine-3'-(succinyl) ester; 5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-deoxyguanosine-3'-succinate; DMT-dG(ibu)-Succinate; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyguanosine-3'-(2-cyanoethyl N,N-diisopropylphosphoramidite) succinate precursor; Ibu-DMT-dG-Succinyl CPG precursor; Modified Deoxyguanosine Derivative
EINECS	Contact for details

Quality Control

Our Ibu-Dmt-Deoxyguanosine Succinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. Use under an inert atmosphere for optimal handling.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.