Description

6α-Methoxy-17β-Estradiol is a synthetic, methoxylated derivative of the natural hormone estradiol. This compound is of significant interest in pharmaceutical research and development, particularly as a key intermediate or reference standard for novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in endocrinology, oncology, and metabolic disease studies.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of advanced steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies investigating estrogen receptor (ER) binding affinity, selectivity, and metabolic pathways.
• Academic & R&D Laboratories: Employed in preclinical research for developing new therapeutic candidates targeting hormone-sensitive conditions.
• Analytical Standard: Provides a high-purity benchmark for quality control and method validation in analytical chemistry (e.g., HPLC, LC-MS).
• Fine Chemical Synthesis: Acts as a specialized starting material for custom synthesis and the production of other modified steroid derivatives.

Basic Information

Product Name	6α-Methoxy-17β-Estradiol
CAS No.	74312-88-2
Molecular Formula	C19H26O3
Molecular Weight	302.41 g/mol
Synonyms	6-Methoxyestra-1,3,5(10)-triene-3,17β-diol; 6-Methoxy-17β-estradiol; 6α-Methoxyestradiol; 6-Methoxy-E2; Estra-1,3,5(10)-triene-3,17β-diol, 6-methoxy-; 6-Methoxy-17β-oestradiol
EINECS	Contact for details

Quality Control

Our 6α-Methoxy-17β-Estradiol is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Quality is verified against established in-house specifications using advanced techniques such as HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.