Description

Cytidine 2',3'-Cyclic Monophosphate, Barium Salt is a specialized nucleotide derivative where the phosphate group forms a cyclic ester with the 2' and 3' hydroxyl groups of the ribose sugar, stabilized as a barium salt. This molecular configuration is of significant interest in biochemical research, particularly in the study of RNA structure, stability, and enzymatic hydrolysis pathways. It serves as a critical reference standard and synthetic intermediate for pharmaceutical R&D, diagnostic reagent development, and academic laboratories focused on nucleic acid chemistry and metabolism.

Application

• Biochemical Research Standard: Used as a high-purity reference compound for calibrating analytical instruments (HPLC, NMR) and studying RNA hydrolysis mechanisms.
• Pharmaceutical Intermediate: Acts as a key building block in the synthesis of novel nucleoside analogs and potential antiviral or anticancer prodrugs.
• Enzymology Studies: Serves as a specific substrate for investigating the activity and kinetics of ribonucleases (RNases) and phosphodiesterases.
• Diagnostic Reagent Development: Employed in the formulation of kits and assays for detecting specific enzymatic activities or for metabolic pathway analysis.
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental studies on nucleotide cyclic phosphate chemistry and cell signaling.

Basic Information

Product Name	Cytidine 2',3'-Cyclic Monophosphate, Barium Salt
CAS No.	74263-38-0
Molecular Formula	C9H11BaN3O8P
Molecular Weight	440.52 g/mol
Synonyms	Cytidine 2',3'-cyclic monophosphate barium salt; 2',3'-cCMP barium salt; Barium cytidine 2',3'-cyclic phosphate; Cytidine 2',3'-cyclic phosphate barium salt; 1-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3,4-dihydro-2H-furan-2-yl]-4-amino-2(1H)-pyrimidinone 2,3-cyclic phosphate barium salt; Cytidine 2':3'-cyclic monophosphoric acid barium salt; cCMP-Ba
EINECS	Contact for details

Quality Control

Our Cytidine 2',3'-Cyclic Monophosphate, Barium Salt is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and ICP-MS for heavy metal and barium content verification. A Certificate of Analysis (COA) detailing all test results is provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a desiccated environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Barium Content (ICP)	Conforms to theoretical value
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.