Description

3,15β-Bis(Trimethylsiloxy)-1,3,5(10)-Estratrien-17-One is a key organosilicon-protected derivative of estratrien-17-one, a steroidal core structure. This compound is valued as a crucial synthetic intermediate in the production of high-value pharmaceutical and fine chemical products. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and advanced organic synthesis sectors for developing novel therapeutic agents and complex molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.
• Fine Chemical Synthesis: Serves as a protected precursor for the preparation of complex, high-purity specialty chemicals.
• Bioconjugate Chemistry: Potential use in the development of steroid-protein conjugates for diagnostic or therapeutic applications.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for commercial manufacturing.

Basic Information

Product Name	3,15β-Bis(Trimethylsiloxy)-1,3,5(10)-Estratrien-17-One
CAS No.	74231-49-5
Molecular Formula	C24H42O3Si2
Molecular Weight	434.77 g/mol
Synonyms	3,15β-Bis(trimethylsilyloxy)estra-1,3,5(10)-trien-17-one; 3,15β-Bis-O-(trimethylsilyl)estra-1,3,5(10)-trien-17-one; 17-Oxoestra-1,3,5(10)-triene-3,15β-diyl bis(trimethylsilyl) ether; Estratrien-17-one, 3,15β-bis(trimethylsiloxy)-; 3,15β-Di-O-trimethylsilyl-estra-1,3,5(10)-trien-17-one
EINECS	Contact for details

Quality Control

Our 3,15β-Bis(Trimethylsiloxy)-1,3,5(10)-Estratrien-17-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.