Description

Doxazosin CAS NO 74191-85-8 is a selective α-1 adrenergic receptor antagonist belonging to the quinazoline chemical class. This compound is of critical importance as the active pharmaceutical ingredient (API) in medications used to manage hypertension and benign prostatic hyperplasia (BPH). It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of cardiovascular and urological therapeutics. Our supply ensures high purity and consistent quality to meet stringent Good Manufacturing Practice (GMP) standards.

Application

• Active Pharmaceutical Ingredient (API) in antihypertensive medications.
• Core component in formulations for the treatment of Benign Prostatic Hyperplasia (BPH).
• Reference standard for analytical method development and quality control in pharmaceutical laboratories.
• Key intermediate in advanced pharmaceutical research and new drug development.
• Raw material for the synthesis of related quinazoline derivatives in medicinal chemistry.
• Used in clinical research studies and bioavailability testing.

Basic Information

Product Name	Doxazosin
CAS No.	74191-85-8
Molecular Formula	C23H25N5O5
Molecular Weight	451.48 g/mol
Synonyms	Doxazosin Mesylate; UK-33274; Doxazosinum; 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine; Cardura; Alfadil; Doxacard; Doxapress
EINECS	Contact for details

Quality Control

Our Doxazosin is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant pharmacopeial standards (USP/EP) and our quality management system is designed to support regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities NMT 1.0% Any individual impurity NMT 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.