Description

3-Thiazolidinecarbonyl Chloride, 2-Thioxo- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its high reactivity, particularly as an acylating agent, makes it invaluable for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of thiazolidine-based drug candidates, including potential enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Peptide Mimetics & Conjugation: Employed for introducing the 2-thioxothiazolidine moiety into peptides or other biomolecules to alter properties or create bioconjugates.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical resistance.
• Chemical Biology Probes: Useful for synthesizing activity-based probes to study enzyme function and mechanism in biological systems.
• Ligand Synthesis for Catalysis: Serves as a starting material for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Thiazolidinecarbonyl Chloride, 2-Thioxo- (9Ci)
CAS No.	74179-13-8
Molecular Formula	C4H4ClNOS2
Molecular Weight	181.66 g/mol
Synonyms	2-Thioxo-1,3-thiazolidine-4-carbonyl chloride; 2-Thioxo-4-thiazolidinecarbonyl chloride; 4-Chlorocarbonyl-2-thioxothiazolidine; 2-Mercaptothiazoline-4-carbonyl chloride; Rhodanine-4-carbonyl chloride; 2-Thioxothiazolidine-4-carboxylic acid chloride; 2-Sulfanylidene-1,3-thiazolidine-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Thiazolidinecarbonyl Chloride, 2-Thioxo- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized by multiple analytical techniques, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.