Description

5-(2-Bromovinyl)-2'-Deoxycytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily utilized by research institutions, pharmaceutical companies, and biotechnology firms engaged in the development of nucleoside-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Antiviral Drug Research: A key synthetic intermediate in the development of nucleoside analogs targeting viral polymerases.
• Oncology Research: Used in the synthesis of potential chemotherapeutic agents that act as DNA synthesis inhibitors.
• Biochemical Probes: Serves as a modified base for creating labeled nucleotides used in molecular biology and diagnostic assays.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Academic Research: Employed in universities and research institutes for studying enzyme mechanisms and nucleic acid chemistry.
• Process Development: Used by chemical manufacturers for scaling up the synthesis of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	5-(2-Bromovinyl)-2'-Deoxycytidine
CAS No.	74131-09-2
Molecular Formula	C11H14BrN3O4
Molecular Weight	332.15 g/mol
Synonyms	5-(2-Bromovinyl)-2'-deoxycytidine; 5-[(E)-2-Bromovinyl]-2'-deoxycytidine; (E)-5-(2-Bromovinyl)-2'-deoxycytidine; 2'-Deoxy-5-(2-bromovinyl)cytidine; BVDU; Brivudine Impurity; Brivudine Related Compound; Nucleoside Analog
EINECS	Contact for details

Quality Control

Our 5-(2-Bromovinyl)-2'-Deoxycytidine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients in pharmaceutical and biotechnology sectors.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.