Description

Propanoyl Bromide, 2-Oxo- is a highly reactive acyl bromide derivative, specifically an α-keto acid bromide, with the CAS number 74100-44-0. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 2-oxopropanoyl functional group. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, including heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key reagent for the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly in constructing peptide mimetics and heterocyclic cores.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive bromide facilitates the creation of novel active compounds.
• Peptide Chemistry & Bioconjugation: Acts as an efficient acylating agent for modifying amino acids, peptides, and proteins in research and bioconjugate development.
• Material Science & Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of specialized polymers and functional materials.
• Organic Synthesis & Research: A versatile reagent for Friedel-Crafts acylation, nucleophilic substitution, and other reactions to introduce keto-acid functionalities.
• Fine Chemical Manufacturing: Integral in the multi-step synthesis of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Propanoyl Bromide, 2-Oxo-
CAS No.	74100-44-0
Molecular Formula	C3H3BrO2
Molecular Weight	150.96 g/mol
Synonyms	Pyruvoyl Bromide; 2-Oxopropanoyl Bromide; α-Ketopropionyl Bromide; Pyruvic Acid Bromide; Bromopyruvic Acid Bromide; 2-Oxopropanoic Acid Bromide; Propanoyl bromide, 2-oxo-; 74100-44-0
EINECS	Contact for details

Quality Control

Every batch of Propanoyl Bromide, 2-Oxo- is manufactured and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.