Description

9,11-Anhydro-12-Hydroxy Fusidic Acid CAS NO 74048-44-5 is a key semi-synthetic derivative of fusidic acid, a potent antibiotic belonging to the fusidane class. This compound is valued for its enhanced chemical stability and serves as a critical intermediate in the synthesis of advanced pharmaceutical agents. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing novel antibacterial therapies and studying bacterial protein synthesis inhibition.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of next-generation fusidic acid derivatives and novel antibiotic formulations.
• Antibacterial Research: Used in microbiological and biochemical research to investigate mechanisms of action against Gram-positive bacteria, including MRSA (Methicillin-resistant *Staphylococcus aureus*).
• Reference Standard: Serves as a high-purity chemical reference standard (CRS) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• API Development: Employed in the research and development of new Active Pharmaceutical Ingredients (APIs) targeting bacterial infections.
• Biochemical Studies: Utilized in studies exploring protein synthesis inhibition at the ribosomal level.

Basic Information

Product Name	9,11-Anhydro-12-Hydroxy Fusidic Acid
CAS No.	74048-44-5
Molecular Formula	C31H48O6
Molecular Weight	516.72 g/mol
Synonyms	9,11-Anhydro-12-hydroxyfusidic acid; 12-Hydroxy-9,11-anhydrofusidic Acid; Fusidic Acid Impurity; Fusidic Acid Derivative; 3α,11α,16β-Triacetoxy-29-nor-8α,9β,13α,14β-fusida-17(20),24-dien-21-oic Acid; (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(Acetyloxy)-3,11-dihydroxy-29-nor-8,9:11,13-diepoxy-14,15-seco-5α,9β,13α,14β-cholesta-17(20),24-dien-21-oic Acid γ-Lactone 4-Acetate
EINECS	Contact for details

Quality Control

Our 9,11-Anhydro-12-Hydroxy Fusidic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.