Description

(R)-α-Aminocyclohexadieneacetyl Chloride Hydrochloride is a high-purity chiral building block and key synthetic intermediate. Its value lies in providing a stereochemically defined, reactive handle for constructing complex molecules, particularly in the synthesis of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular architecture for their development pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral drugs, especially those targeting the central nervous system (CNS) or possessing complex cyclic structures.
• Agrochemical Synthesis: Used in the research and development of novel, stereoselective pesticides and herbicides.
• Peptide Mimetics & Conjugate Chemistry: Serves as an acylating agent for introducing the (R)-α-aminocyclohexadieneacetyl moiety into peptides or other biomolecules to modify their properties.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development of new catalytic systems for asymmetric synthesis.
• Advanced Material Precursor: Potential use in the synthesis of specialized polymers or organic frameworks with tailored chiral properties.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring high chemical and optical purity.

Basic Information

Product Name	(R)-α-Aminocyclohexadieneacetyl Chloride Hydrochloride
CAS No.	74009-52-2
Molecular Formula	C8H11Cl2NO
Molecular Weight	208.08 g/mol
Synonyms	(R)-1-Amino-1-cyclohexa-2,4-dien-1-ylacetyl chloride hydrochloride; (R)-α-Aminocyclohexa-2,4-dien-1-ylacetyl chloride HCl; (1R)-1-Amino-1-cyclohexa-2,4-dien-1-ylacetyl chloride hydrochloride; (R)-Cyclohexadienylglycyl chloride hydrochloride; (R)-Aminocyclohexadienylacetyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-α-Aminocyclohexadieneacetyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis (HPLC), to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.