Description

[1S,5R,(+)]-8-Propyl-8-Azabicyclo[3.2.1]Octane-2β-Ol Diphenylhydroxyacetate is a high-purity, stereochemically defined tropane alkaloid derivative. This compound is valued for its role as a key chiral intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and for analytical method development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Reference Standard: Used in analytical laboratories for method validation, quality control, and impurity profiling via HPLC, GC, or LC-MS.
• Medicinal Chemistry Research: Serves as a scaffold or precursor in structure-activity relationship (SAR) studies for novel therapeutic agents.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of tropane-based pharmaceuticals.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis, asymmetric catalysis, and neuropharmacology.

Basic Information

Product Name	[1S,5R,(+)]-8-Propyl-8-Azabicyclo[3.2.1]Octane-2β-Ol Diphenylhydroxyacetate
CAS No.	73889-52-8
Molecular Formula	C24H29NO3
Molecular Weight	379.50 g/mol
Synonyms	(+)-8-Propyl-8-azabicyclo[3.2.1]octan-2β-ol diphenylhydroxyacetate; 2β-Hydroxy-8-propylnortropane diphenylglycolate; Tropane-2β-ol, 8-propyl-, diphenylhydroxyacetate, (1S,5R)-; Diphenylglycolic acid 8-propylnortropan-2β-yl ester; 73889-52-8; (1S,5R)-(+)-8-Propyl-8-azabicyclo[3.2.1]octan-2-ol diphenylglycolate
EINECS	Contact for details

Quality Control

Our [1S,5R,(+)]-8-Propyl-8-Azabicyclo[3.2.1]Octane-2β-Ol Diphenylhydroxyacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and purity meet exacting standards. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.