Description

(-)-(S)-1-<4-(Trifluoromethyl)Phenyl>Propan-1-Ol CAS NO 73854-05-4 is a high-purity chiral alcohol building block characterized by its trifluoromethylphenyl group and (S)-configuration. This compound is a critical intermediate in the synthesis of advanced pharmaceutical ingredients and agrochemicals, where its defined stereochemistry and fluorine substitution are essential for biological activity and metabolic stability. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active compounds and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals due to its aromatic and fluorinated structure.
• Fine Chemical Production: Acts as a building block for various high-value specialty chemicals and flavors & fragrances.

Basic Information

Product Name	(-)-(S)-1-<4-(Trifluoromethyl)Phenyl>Propan-1-Ol
CAS No.	73854-05-4
Molecular Formula	C10H11F3O
Molecular Weight	204.19 g/mol
Synonyms	(S)-1-[4-(Trifluoromethyl)phenyl]propan-1-ol; (S)-α-Ethyl-4-(trifluoromethyl)benzenemethanol; (-)-(S)-1-(4-Trifluoromethylphenyl)-1-propanol; (S)-1-(4-Trifluoromethylphenyl)propanol; (S)-α-Ethyl-α-(trifluoromethyl)benzyl alcohol; (S)-TFMPP; (S)-4-(Trifluoromethyl)phenyl ethyl carbinol
EINECS	Contact for details

Quality Control

Our (-)-(S)-1-<4-(Trifluoromethyl)Phenyl>Propan-1-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.