Description

3-α-Ethoxycarbonyl-12-α-Hydroxy-7-Oxocholan-24-Oic Acid, Methyl Ester is a high-purity, synthetic steroidal derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chemical intermediate for the synthesis of complex bioactive molecules, offering precise structural control for medicinal chemists. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for investigating structure-activity relationships (SAR) and developing new therapeutic candidates.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial manufacturing of complex organic molecules.
• Biochemical Research: Utilized in studies targeting bile acid metabolism, nuclear receptor modulation, and related metabolic pathways.

Basic Information

Product Name	3-α-Ethoxycarbonyl-12-α-Hydroxy-7-Oxocholan-24-Oic Acid, Methyl Ester
CAS No.	73771-71-8
Molecular Formula	C28H44O7
Molecular Weight	492.65 g/mol
Synonyms	Methyl 3α-Ethoxycarbonyl-12α-Hydroxy-7-Oxocholan-24-Oate; 7-Oxolithocholic Acid 3-Ethyl Ester Methyl Ester; 3α-(Ethoxycarbonyl)-12α-Hydroxy-7-Oxo-5β-Cholan-24-Oic Acid Methyl Ester; 3α-Ethoxycarbonyl-12α-Hydroxy-7-Oxo-5β-Cholan-24-Oic Acid Methyl Ester; 7-Ketolithocholic Acid 3-Ethyl Ester Methyl Ester; 3-Ethoxycarbonyl-12-Hydroxy-7-Oxocholan-24-Oic Acid Methyl Ester; Methyl 3α-Ethoxycarbonyl-12α-Hydroxy-7-Oxo-5β-Cholan-24-Oate
EINECS	Contact for details

Quality Control

Our 3-α-Ethoxycarbonyl-12-α-Hydroxy-7-Oxocholan-24-Oic Acid, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.