Description

Prednicarbate is a synthetic corticosteroid ester specifically designed for topical application. This compound matters for its potent anti-inflammatory and anti-pruritic properties, making it a key active pharmaceutical ingredient (API) in dermatological formulations. It is primarily needed by pharmaceutical manufacturers developing creams, ointments, and lotions for the treatment of various inflammatory skin conditions such as eczema, psoriasis, and contact dermatitis.

Application

• Primary Active Pharmaceutical Ingredient (API) in topical corticosteroid creams and ointments.
• Formulation of prescription dermatological products for treating eczema (atopic dermatitis).
• Key component in anti-inflammatory medications for psoriasis management.
• Use in specialized lotions for severe contact dermatitis and allergic skin reactions.
• Base material for compounding pharmacies preparing customized topical steroid formulations.
• Research and development of novel transdermal drug delivery systems.

Basic Information

Product Name	Prednicarbate
CAS No.	73771-04-7
Molecular Formula	C27H36O8
Molecular Weight	488.57 g/mol
Synonyms	Prednicarbate; (11β)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione 17-(ethyl carbonate) 21-propanoate; 17α-Ethoxycarbonyloxy-11β-hydroxy-21-propionyloxy-1,4-pregnadiene-3,20-dione; Dermatop; Dermatop®; Prednitop
EINECS	Contact for details

Quality Control

Our Prednicarbate is manufactured under strict quality management systems, targeting compliance with pharmaceutical grade standards such as ICH Q7 and relevant pharmacopoeial guidelines. Each batch undergoes comprehensive analytical testing including identity, purity, and impurity profile verification. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and quality assurance for our B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Water (Karl Fischer)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.