Description

Ethyl 4-Isothiocyanatopiperidine-1-Carboxylate is a versatile piperidine derivative functionalized with both an isothiocyanate and an ethyl carbamate group. This bifunctional nature makes it a valuable key intermediate in organic synthesis, particularly for constructing complex molecules with specific biological activity. It is primarily sought by pharmaceutical research and agrochemical development teams for use in medicinal chemistry and as a building block for advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents, enzyme inhibitors, and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isothiocyanate moiety can act as a reactive handle.
• Chemical Biology Probe Development: Serves as a scaffold for creating activity-based probes (ABPs) to study enzyme function and protein interactions within biological systems.
• Peptidomimetics & Conjugate Chemistry: The reactive isothiocyanate group enables efficient conjugation to amines, making it useful for labeling biomolecules and constructing peptide-like structures.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of specialty polymers and functionalized surfaces.

Basic Information

Product Name	Ethyl 4-Isothiocyanatopiperidine-1-Carboxylate
CAS No.	73733-70-7
Molecular Formula	C9H14N2O2S
Molecular Weight	214.28 g/mol
Synonyms	1-Carbethoxy-4-isothiocyanatopiperidine; Ethyl 4-Isothiocyanato-1-piperidinecarboxylate; 4-Isothiocyanato-1-piperidinecarboxylic Acid Ethyl Ester; 1-Piperidinecarboxylic Acid, 4-Isothiocyanato-, Ethyl Ester; N-Carbethoxy-4-isothiocyanatopiperidine; Ethyl N-(4-Isothiocyanatopiperidin-1-yl)formate; 73733-70-7
EINECS	Contact for details

Quality Control

Our Ethyl 4-Isothiocyanatopiperidine-1-Carboxylate is manufactured under strict quality protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.