Description

4-Fluoro-α-Methyl-α-(1-Methylcyclopropyl)Benzyl Alcohol is a high-value fluorinated organic intermediate characterized by its unique sterically hindered benzyl alcohol structure. This compound is essential for the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern imparts critical biological activity and metabolic stability. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atom and cyclopropyl group enhance bioactivity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with tailored optical or surface properties.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions due to its fluorinated label.

Basic Information

Product Name	4-Fluoro-α-Methyl-α-(1-Methylcyclopropyl)Benzyl Alcohol
CAS No.	73728-62-8
Molecular Formula	C12H15FO
Molecular Weight	194.25 g/mol
Synonyms	α-Methyl-α-(1-methylcyclopropyl)-4-fluorobenzyl alcohol; 1-(4-Fluorophenyl)-1-(1-methylcyclopropyl)ethanol; 4-Fluoro-α-methyl-α-(1-methylcyclopropyl)benzenemethanol; (4-Fluorophenyl)(1-methylcyclopropyl)methyl ethanol; Benzyl alcohol, 4-fluoro-α-methyl-α-(1-methylcyclopropyl)-; 73728-62-8; (RS)-1-(4-Fluorophenyl)-1-(1-methylcyclopropyl)ethanol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-α-Methyl-α-(1-Methylcyclopropyl)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and agrochemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as required)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.