Description

2-Pyridinecarbonyl Bromide, 6-Methyl- (9Ci) is a versatile and reactive brominated heterocyclic building block. This compound matters for its role as a key acylating agent and intermediate in the synthesis of complex molecules, enabling the introduction of the 6-methylpicolinoyl moiety. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the picolinoyl group can confer specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that incorporate pyridine-based units.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Pyridinecarbonyl Bromide, 6-Methyl- (9Ci)
CAS No.	73691-25-5
Molecular Formula	C7H6BrNO
Molecular Weight	200.04 g/mol
Synonyms	6-Methylpicolinoyl Bromide; 6-Methylpyridine-2-carbonyl Bromide; 2-Bromocarbonyl-6-methylpyridine; 6-Methyl-2-pyridinecarbonyl Bromide; 6-Methylpicolinic Acid Bromide; 6-Methylpyridine-2-carboxylic Acid Bromide; α-Bromo-6-methylpicolinaldehyde (tautomer); 2-Carboxy-6-methylpyridine Bromide
EINECS	Contact for details

Quality Control

Our 2-Pyridinecarbonyl Bromide, 6-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.